1、辽宁省教育厅项目: 计算机模拟中药有效成分抗流感病毒机理研究，结题 。

2、辽宁省科技厅项目: 纳豆激酶溶栓活性及其定点突变的研究，结题 。

3、辽宁省教育厅和社科联百项课题项目: 大数据时代给我省经济带来的挑战和影响研究 ，结题 。

4、沈阳市科技局项目: H5N1禽流感NS1蛋白与人NOLC1蛋白的相互作用机制研究 ，在研。

5、沈阳市科技局项目: 基于机器学习和分子对接方法大规模虚拟筛选流感病毒神经氨酸酶抑制剂及其生物活性验证研究 ，在研。

1、Li Zhang, Haixin Ai(共同第一作者), Shimeng Li, Mengyuan Qi, Jian Zhao, Qi Zhao and Hongsheng Liu (通讯作者). Virtual screening approach to identifying influenza virusneuraminidase inhibitors using molecular docking combinedwith machine-learning-based scoring function. Oncotarget. 2017, 8(47): 83142–83154.

2、Li Zhang, Haixin Ai(共同第一作者), Wen Chen, Zimo Yin, Huan Hu, Junfeng Zhu, Jian Zhao, Qi Zhao, Hongsheng Liu(通讯作者). CarcinoPred-EL: Novel models for predicting the carcinogenicity of chemicals using molecular fingerprints and ensemble learning methods. Scientific Reports. 2017, 7(1), 2118.

3、Haixin Ai, Runlin Wu, Li Zhang, Xuewei Wu, Junchao Ma, Huan Hu, Liangchao Huang, Wen Chen, Jian Zhao, Hongsheng Liu*. pSuc-PseRat: Predicting Lysine Succinylation in Proteins by Exploiting the Ratios of Sequence-Coupling and Properties. Journal Computational Biology. 2017, 24(0):1-10.

4、Li Zhang, Haixin Ai, Qi Zhao, Junfeng Zhu, Wen Chen, Xuewei Wu, Liangchao Huang, Zimo Yin, Jian Zhao, Hongsheng Liu*. Computational Prediction of Influenza Neuraminidase Inhibitors Using Machine Learning Algorithms and Recursive Feature Elimination Method. ISBRA, 2017, LNBI 10330, 344–349.

5、Haixin Ai, Yuchen Che, Li Wang, Li Zhang, Ying Gu, Yanni Tan, Alan K   Chang, Hongsheng Liu*. Paenibacillus liaoningensis sp. nov., isolated from soil. International Journal of Systematic and Evolutionary Microbiology. 2016, 66(8):3150-3156.

6、Haixin Ai, Fangliang Zheng, Fangbo Deng, Chunyu Zhu, Ying Gu, Li Zhang, Xuejiao Li, Alan K Chang, Jian Zhao, Junfeng Zhu, Hongsheng Liu*. Structure-Based Virtual Screening for Potential Inhibitors of Influenza A Virus RNA Polymerase PA Subunit. International Journal of Peptide Research and Therapeutics. 2015, 21(1):149-156.

7、Haixin Ai, Li Zhang, Alan K. Chang, Hongyun Wei, Yuchen Che, Hongsheng Liu*. Virtual screening of potential inhibitors from TCM for the CPSF30 binding site on the NS1A protein of influenza A virus. Journal of Molecular Modeling. 2014, 20(3):2142.